Member-only story

Offbase

Colossal is getting paid $200 million to resurrect the Woolly Mammoth

Uncovering the science and business model behind the de-extinction of the Woolly Mammoth

Murto Hilali

--

Image from DALL-E

Abstract

Colossal is resurrecting the Woolly Mammoth by editing Asian elephant DNA to look like a mammoth’s.

Colossal has two business models:

  • Product — selling to conservation orgs & governments.
  • Process — patenting innovations made in their research, licensing their tech to other companies.

Insight: To get paid to drop the ‘fi’ in ‘sci-fi’, you’ll probably need the following:

  • A charismatic protagonist, usually the founder but sometimes the product.
  • Something to pay the bills, like a spin-off business.
  • Tangible outputs from your research, like licensable tech.

Most startup ideas probably shouldn’t exist.

They either:

  • Don’t solve a problem
  • Would do so unprofitably

You’d assume Colossal matches this profile. After all, most people I know are not lamenting the global shortage of woolly mammoths.

And yet the company’s raised over $200 million in funding.

I think Colossal’s story contains an insight (or two) that reveals how aspiring founders can turn high-risk, long-term biotechnology into a feasible, fundable business.

Business

Bessemer Venture Partners created a list of the top 100 deep tech companies in the world (next-gen biotech included).

  • Statistic: The companies were 9.2 years old and had raised over $800 million in VC funding, on average.
  • Signal: It takes a lot of time and money to build a successful deep-tech firm.

Most emerging biotechs fall into the deep tech category and face the same time and money issues:

  • Time: Factors outside of a business’ control can delay and upend timelines. (FDA approval, finding out a hypothesis was wrong).

--

--

No responses yet